Transdermal Hormone Replacement Therapy Report

As life expectancy in the developed world increases and populations age, the incidence and associated morbidity of chronic and acute pain is increasing and placing a higher level of emphasis on pain management as a quality-of-life issue for patients and their families. Responding to this trend, drug developers are increasingly turning to transdermal formulations of pain management drugs. Because it has the potential to improve drug therapy compliance, transdermal delivery addresses a key healthcare issue – one that is particularly problematic in aging populations and developing economies. Currently approved transdermal pain products include narcotics, NSAIDs, and topical anesthetics. These patches and gels will encounter competition from development-stage transdermal formulations for a number of pain medications presently being marketed in oral or parenteral form. Several of these development programs involve international partnerships designed to take advantage of perceived opportunities in regional markets.

Publication Date: January 2010

Summary of Contents (see Prospectus for full Contents)

Executive Summary

Scope and Definitions

The Hormone Replacement Therapy Market

The Opportunity for Transdermal Hormone Replacement Therapy

The Hormone Replacement Therapy Market Opportunity

Evolution in HRT Guidelines

Regional Factors in HRT Practice

Hormone Replacement Therapy Demand Drivers

Competitive Landscape

Factors Limiting Growth

Transdermal Drug Delivery Dynamics

Transdermal HRT Patches

Patch Designs and Construction

Transdermal Patch Manufacturing and Packaging

The Patch Manufacturing Ecosystem

Patch Economics

Transdermal HRT Gels

Transdermal Formulations

IP and Proprietary Technology

Limitations of Topical Gels

Transdermal HRT Sprays

Transdermal HRT Product Assessments and Market Prospects

FDA Approved Transdermal HRT Products

Estradiol

Estradiol Levonorgestrel

Estradiol/Norelgestromin

Estradiol/Progestin

Testosterone

Commercialized Transdermal HRT Products (Non-FDA Approved)

Estradiol

Estradiol/Norethindrone

Development-Stage Transdermal Pain Management Products

Estradiol

Testosterone

Other Hormones

Transdermal Hormone Replacement Therapy Market Factors

Regional Regulations

Clinical Trials

Quality and Reliability

Indications Prescribing Guidelines and Off-Label Prescribing

Managed Care and Payor Initiatives

Rx-to-OTC Switching

Skin Patch Revenue Models

Market Forecasts

Forecast Methodology

Forecasts by Region

Forecasts by Drug Class

Forecasts by Delivery Form Factor

Market Share Data

Market Participant Profiles

About Our Reports

Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.