Greystone Associates

As a group, autoimmune diseases represent one of the most intractable families of conditions facing medical science. The complexities and genetic underpinnings of the human immune response result in a set of disease targets that are at once physiologically ubiquitous and highly individualized. Until recently, autoimmune disease patients were given little hope for an effective treatment. But the convergence an of improved understanding of autoimmune disease mechanisms and the availability of recombinant cytokines has led to systemic treatments that, while not devoid of side effects, have demonstrated the ability to control autoimmune reactions in a significant number of patients. A number of potentially important pipeline drugs hold the promise of future improvements in outcomes for autoimmune disease patients. This study analyzes current autoimmune therapeutics and assesses the next-generation of candidates and their probable impact on treatment options and the competitive landscape.

Publication: April 2010

Summary of Contents

Autoimmune Therapeutic Dynamics

Key Market Drivers

Important Risk Factors

Demographics and Growth

Managed Care Factors

Prescribing Trends

Factors Limiting Growth

Industry Alignment

Competitive Landscape

Biological Therapeutics Assessments

Arthritis

Disease Forms & Immune Mechanisms

Key Approved Biologicals

Development-stage Candidates

Market Factors

Commercial Outlook and Forecasts

Crohn’s Disease

Disease Incidence and Demographics

Current Generation Treatment Options

Therapies in Development

Market Factors

Commercial Outlook and Forecasts

Lupus

Current Treatment Options

Pipeline Candidates

Market Factors

Commercial Outlook and Forecasts

Multiple Sclerosis

Disease Mechanisms & Therapeutic

Strategies

Biologicals for Treating MS

Development-stage Candidates

Market Factors

Commercial Outlook and Forecasts

Psoriasis

Disease Mechanisms & Targets

Prescribing Trends and Drug Efficacy

Market Sector Factors

Development-stage Candidates Commercial Outlook and Forecasts

Autoimmune Therapeutics – Company Profile

About Our Reports

Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.