Electroporation for Gene and DNA Transfection

The evolution of drug development and applied genetics are moving beyond traditional models of administration and creating challenges for medical technologists. By targeting biologicals at the cellular level, researchers are attempting to establish a new generation of therapeutics that has the potential to approach the precision and accuracy envisioned since the commercial introduction of PCR. Numerous programs and clinical trials are involved in the development of direct-to-cell delivery using electroporation, a long-existing technology that has been dusted off and re-invented to support current clinical and research needs. While the majority of electroporation applications are in the research sector, the commercialization of new treatments is expected to create opportunities for sector participants.

Publication Date: April 2010

Summary of Contents (see Prospectus for Full Contents)

Executive Summary

Therapeutic Market Dynamics

Biologicals, Nucleic Acids and Medical Technology

Key Market Drivers

Competitive Landscape

Factors Limiting Growth

Electroporation Technology and Design Factors

Electroporation Capabilities and Limits

Key Performance Issues

Advanced Features

Proprietary Pulse Technology

Dermal/Intradermal vs Intramuscular Delivery

User Interface Factors

Reagents and Kits

Combination Delivery Protocols

Therapeutic Adjuvants

Post-Delivery Electroporation

The Current Market for Electroporation

Research

Pre-Clinical Development/Animal Models

Nonviral Gene Delivery/Transfection

Therapeutics

Physical Medicine

Prophylactic Vaccines

Therapeutic Proteins & Peptides

Therapeutic Vaccines

Current Key Electroporation Application Segments

Oncology Biomarkers

Diagnostics

Therapeutics

Cytokines

DNA Vaccines

Electrochemotherapy

Growth Factors

Important Near-Term Therapeutic Market Sectors

Oncology

Breast

Cervical

Colorectal

Melanoma

Prostate

Infectious Disease

HCV

HIV

Electroporation – Analysis of Commercial Products by Supplier

Market Factors

Government Regulations

Clinical Trials and Endpoints

Third-Party Relationships and Collaborations

Electroporation - Company Profiles

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Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.