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 Drug Delivery: Self-Administration

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  Drug Delivery for Self-Administration: Devices, Drugs, Product Strategies & Forecasts
 

As the trend toward drug combination products for prescription drugs grows, a number of factors are converging to create both risk and opportunity for drug makers and their device partners. These include new classes of drugs for previously refractory conditions, the growing trend toward self-administration for chronic diseases, shifting patient demographics in industrialized countries, and continued pressure to control healthcare costs. The recent escalation in new biological drugs indicated for chronic ailments is placing renewed emphasis on simple and reliable devices for the self administration of prescription drugs. These factors are giving rise to a new generation of sophisticated, application-specific drug delivery devices designed to satisfy caregiver and patient preferences while addressing managed care initiatives and the limitations of new classes of therapeutic drugs. User-friendly designs and the availability of an increasing number of drug combination products are propelling acceptance of user friendly combination products at the expense of other drug delivery methods. Because of their ability to safely and reliably satisfy treatment protocols and compliance goals, drug combination products will have a significant impact on the future of drug combination products for self administration.

Publication Date: September 2009

Table of Contents

Text Box: Table of Contents
 

 

Executive Summary

 

Drug Delivery Market Dynamics

 

Technology and Patient-Friendly Therapeutics

The Impact of Self-Administration

Market Drivers and Risk Factors

Competitive Landscape

 

I.  Injectable Drug Delivery

 

Injectable Drug Delivery Sector Overview

 

Caregiver Preferences and Expectations

Growth Factors

    The Growth of Self-Administration for Chronic Conditions

        Managed Care Trends

        End-User Preferences and Expectations

    Recombinant Proteins and Antibody Drugs

 

Injectable Drug Delivery Segment Analysis

 

Traditional Syringes

    Supply Chain Overview

    Technology Leaders

    Key Buyer/End User Factors

    Historical Market Data

    Traditional Syringe Company Profiles

Safety Syringes

    Factors Driving Safety Syringe Growth

    Safety Syringe Device Design Analysis

        Auto disable

        Manual Disable

        Auto and Manual Retractable

    The Leaders – Safety Syringe Company Profiles

Needle-free Injectors

    Disposable vs. Reusable

    Prefilled vs vials

    The Leaders – Needle-free Company Profiles

Pen Injectors

    Reusable Pens

    Disposable Pens

    Multifunction Autoinjectors

    The Leaders – Pen Injector Company Profiles

 

Injectable Drug Delivery Market Factors

 

Regulatory Factors

Technology Factors

Formulation Factors             

Geographic Factors

 

Assessment of Important Self-Administration Therapeutics Segments

 

Arthritis

Cancer

Diabetes

Hepatitis

Human Growth Hormone

Multiple Sclerosis

Vaccines

 

II. Inhaled Drug Delivery

 

Inhaled Drug Delivery Sector Overview

 

The Upper Respiratory Market

The Systemic/Deep Lung Market

Established Therapeutic Targets

Emerging Therapies

Competing Technologies

 

Inhalation Technology

 

Product Design Factors

Inhaler Designs

    Dry Powder Inhalers

        Powder Technology

        Packaging Issues

        DPI Device Company Profiles

    Metered Dose Inhalers

        Basic Designs

        Breathe Actuated Designs

        MDI Device Company Profiles

    Nebulizers

        Nebulizer Device Company Profiles

Performance Factors

    Bioavailability

    Dose Reproducibility

    Active Compound Stability

Commercial Devices

Development-Stage Devices

 

Inhaled Drug Delivery Therapeutic Segment Analysis

 

Allergic Rhinitis

Asthma

Cancer

Chronic Obstructive Pulmonary Disease

Cystic Fibrosis

Diabetes

Hemophilia

Hereditary Diseases

Hormone Therapy/Replacement

Immune System Modulators

Multiple Sclerosis

Neurology

Osteoporosis

Pain Management

Sexual Health

 

Inhaled Drug Delivery Market Factors       

 

FDA Regulations

Device Packaging

Design Partnerships


 

III. Transdermal Drug Delivery

 

Prescription Patch Market Dynamics

 

Traditional Patch Markets

Recent and Emerging Markets

Transdermal Patch Market Drivers

 

Prescription Patch Design & Technology

 

Passive Patch Architecture

Passive Transdermal Patch Design

Passive Patch Construction

Active Transport Patch Technologies

  Electrical Current

      Iontophoresis

      Electroporation

  Microporation

      Laser Ablation

      Mechanical Arrays

      Radio Frequency

Thermal/Heat

Ultrasound

 

Prescription Patch Development Factors

 

The Design Cycle

Skin Patch Economics

Patch Manufacturing Dynamics

Patch Manufacturing Company Profiles

Patch Product Company Profiles

 

FDA-Approved Patch Therapies – Analysis and Market Data

 

ADHD

Contraception

Cardiovascular/Angina

Depression

Hormone Replacement Therapy

Hypertension

Local Anesthetics

Motion Sickness

Osteoporosis

Pain Management

 

Emerging Patch Therapeutics – Opportunity and Risk Assessment

 

Alzheimer’s

Asthma

Diabetes

Parkinson’s Disease

Sexual Dysfunction

Vaccines

 

Transdermal Patch Market Factors

 

FDA Regulations

Rx-to-OTC Switching

New Patch Technologies

Skin Patch Revenue Models

 

About Our Reports

Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.