Continuous Glucose Monitors and Glycemic Control

The convergence of small-scale electronics and sophisticated biocompatible product designs is giving hope for a better future to millions of diabetes patients worldwide. Continuous glucose monitors that are designed to be implanted and can continually measure glucose levels have the capability to improve glycemic control and patient wellbeing. By integrating the sensing element, electronics, and a power source in a single package, implantable monitors are creating new options for caregivers and their diabetes patients. Signal processing improvements - include improved signal-to-noise ratios and interference filtering - will continue to be critical to the commercialization prospects of implantable monitors. While the potential is substantial, for most participants the road to commercialization will contain numerous speed bumps and delays that will strain capitalization requirements and investor patience. Successful players will be those that realize the value of partnerships and strategic alliances.

Publication Date: July 2010

Table of Contents

Executive Summary

Diabetes Management Market Overview

Diabetes Economics

Monitoring Glucose Levels

Key Factors in Patient Compliance

Market Drivers

Industry Alignment and Competitive Landscape

Glucose Measurement Technologies – Risk & Opportunity Assessment

Electrochemical

Hydrogels

Membranes

Optical

Photoacoustic

Viscosity

Important Research Programs

Technology Factors and their Commercial Impact

Calibration

Accuracy/Precision

Sensor Life

Sensitivity

Sensor Technology & Signal Processing Advances

Factors Driving Monitor Design

Durability/Reliability

Data Collection & Display

Measurement Frequency

Sensor Insertion

Patient/User Interface

Wireless Range

Monitor-Insulin Pump Integration

Market Factors

Medical Device Approval

Clinical Trials

Standards, Regulations and Guidance

Patient/Consumer Sentiment

Design Partnerships

Diabetes Population Demographics

FDA-Approved Continuous Glucose Monitors

DexCom 7 Plus (DexCom)

Freestyle Navigator (Abbott)

Guardian RT (Medtronic)

Paradigm (Medtronic)

Development-Stage Continuous Monitors

Profiles & Commercialization Prospects for Eleven Device Candidates

Continuous Glucose Monitors – Company Profiles

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Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.