Buccal Drug Delivery and Transdermal Technology

In their search for alternative delivery methods that will enhance compliance and improve safety, drug developers and researchers are discovering that the permeability of mucous membranes provides a convenient route for the systemic delivery of new and existing therapeutic drugs. Transmucosal delivery offers the potential for once daily dosing of oral drugs and avoids the effects of first pass metabolism. On the provider side, the development of alternative methods of drug administration has improved the ability of physicians to manage specific problems. Practitioners now recognize the rapid onset, relative reliability, and the general lack of patient discomfort when drugs are administered by the transmucosal route. We expect this market to experience healthy growth through 2012 as buccal technology is applied to existing drugs and as transmucosal formulations become an important route of administration for an increasing number of new NCEs. Growth in this sector will also be driven by the pressure to extend market protection for numerous existing drugs with soon-to-expire patents, and Rx-to-OTC switching.

Publication Date: January 2010

Summary of Contents (see Prospectus for full Contents)

Executive Summary

Drug Delivery Market Dynamics

Pipeline Drugs and Drug Delivery Technology

Formulation Technology Creating Commercial Opportunities

Market and Demand Drivers

Shifting Patient Demographics

The Growth of Self-administration

Drug Discovery Trends

Managed Care Initiatives

Factors Limiting Growth

Competitive Landscape

Competing Transmucosal Drug Delivery Technologies

Oral Sprays

Buccal Films and Tablets

Sublingual Films and Wafers

Commercial Delivery Platforms

Assessment of Commercially Important Buccal Markets

Addiction

Anti-infectives

Cardiology

Neurology

Anti-Emetic

Insomnia

Migraine

Parkinson’s Disease

Spasticity

Pain Management

Sexual Health

Vaccines

FDA-Approved Buccal Drug Products

Product Assessments

Commercial Status

Market Position and Competitive Outlook

Late-Stage Development Buccal Candidate Assessment

Derivative Products

Novel APIs and Indications

Commercial Prospects and Challenges

Buccal Drug Delivery - Business Factors & Strategies

Product Development Issues

Clinical Trial Factors

Formulations and Proprietary Platforms

Patent Expiration and Rx-to-OTC Switching

The Importance of Strategic Relationships

Market Participant Profiles

About Our Reports

Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.