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 Disease Therapeutics: Autoimmune Disease Therapeutics

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Autoimmune Disease Therapeutics: Targets, Technologies, Therapies, Markets & Opportunities
 

As a group, autoimmune diseases represent one of the most intractable families of conditions facing medical science. The complexities and genetic underpinnings of the human immune response result in a set of disease targets that are at once physiologically ubiquitous and highly individualized. Until recently, autoimmune disease patients were given little hope for an effective treatment. But the convergence an of improved understanding of autoimmune disease mechanisms and the availability of recombinant cytokines has led to systemic treatments that, while not devoid of side effects, have demonstrated the ability to control autoimmune reactions in a significant number of patients.  A number of potentially important pipeline drugs hold the promise of future improvements in outcomes for autoimmune disease patients. This study analyzes current autoimmune therapeutics and assesses the next-generation of candidates and their probable impact on treatment options and the competitive landscape.

Publication: August 2009

Summary of Contents (see Prospectus for Full Contents)

Executive Summary

 

Autoimmune Therapeutics Segment Dynamics

 

Evolving Models of Disease and Human Health

Key Market Drivers and Risk Factors

Patient Demographics and Growth

Chronic Disease and Self-administration

Managed Care and Prescribing Trends

Factors Limiting Growth

Industry Alignment and Competitive Landscape

 

Autoimmune Therapeutic Market Assessments

 

Arthritis

Disease Forms and Immune Mechanisms

Therapeutic Strategies

Disease Demographics and Growth

Key Approved Therapies     

Prescribing Trends

Development-stage Candidate Assessment

Market Factors

Commercial Outlook and Forecasts

 

Crohn’s Disease

 Disease Incidence and Demographics

 The Limitations of Screening and Diagnosis

 Current Generation Treatment Options

 Therapies in Development

 Market Factors

 Commercial Outlook and Forecasts

 

Diabetes

 Restoring Islet Cell Function

 Therapies in Development

 Commercial Outlook and Forecasts

 

Lupus

The Ongoing Unmet Need

Difficult to Diagnose – Difficult to Treat

Current Treatment Options are Sparse

Moving Beyond Corticosteroids

Pipeline Candidates – A Ray of Hope

Market Factors

Commercial Outlook and Forecasts

 

Multiple Sclerosis

Disease Mechanisms and Therapeutic Strategies

The Market Opportunity

Competitive Landscape               

The Success of Interferons

The Versatility of Antimetabolites

Approved Therapy Assessment

Development-stage Candidate Assessment

Market Factors

Commercial Outlook and Forecasts

 

Psoriasis

Disease Mechanisms and Therapeutic Targets

Therapeutic Options and Expanded Indications

Prescribing Trends and Drug Efficacy

Market Sector Factors and Recent Developments

Development-stage Candidate Assessment

Commercial Outlook and Forecasts

 

Risk Factors

Clinical Trial Factors

  Patient Enrollment and Genotype Diversity

  Establishing Realistic Endpoints

  Heterogeneous Disease Targets

Product Issues

  Competing with Generics

  Packaging for Self- Administration

Patient Acceptance Issues

  Drug Safety Profiles

  Side Effects and Compliance

     

Autoimmune Therapeutics – Company Profile

 

 
About Our Reports

Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace.